# DirectAnswersRx
> Plain-English answers to GLP-1, hair, ED, and NAD+ questions — with sources you can check.

Excerpts only. Full answers are at the canonical URL below each entry and at the .md twin at that URL + ".md".

## Answers
- [How do GLP-1 medications compare to other weight loss drugs?](https://directanswersrx.com/answers/glp1-vs-other-weight-loss-drugs): As of the mid-2020s, GLP-1–based medications generally help people lose more weight on average than older long-term weight-loss drugs, but they are usually more expensive, often given as injections rather than pills, and may need to be continued to keep the weight off.
- [How much does Zepbound cost without insurance?](https://directanswersrx.com/answers/cost-of-zepbound-without-insurance): As of 2024, Eli Lilly's U.S. list price for Zepbound is $499 to $1,086.37 per fill for a one-month supply, depending on dose and whether the patient buys the single-dose vial through LillyDirect or a pen at retail — with Sen. Bernie Sanders publicly warning on the official Senate.gov site that even …
- [How much does Wegovy cost without insurance?](https://directanswersrx.com/answers/cost-of-wegovy-without-insurance): As of 2024, Wegovy's U.S. list price is about $1,349 for a one-month supply — substantially more than older weight-loss medications and far higher than list prices reported for the same molecule in Denmark, Germany, and the United Kingdom, a gap the Senate HELP Committee entered into the public reco…
- [Semaglutide vs tirzepatide: which is more effective for weight loss?](https://directanswersrx.com/answers/semaglutide-vs-tirzepatide): In the head-to-head SURMOUNT-5 trial published in the New England Journal of Medicine in 2025, tirzepatide produced greater average weight loss than semaglutide over 72 weeks — about 20.2% of baseline body weight with tirzepatide versus 13.7% with semaglutide, in adults with obesity but without type…
- [How much does Ozempic cost without insurance in the United States?](https://directanswersrx.com/answers/cost-of-ozempic-without-insurance): As of 2024, Ozempic's U.S. list price is about $968 for a one-month supply — roughly 10 to 15 times what Novo Nordisk charges in other wealthy countries, a gap the Senate HELP Committee brought to a public hearing on September 24, 2024.
- [What are the most common side effects of GLP-1 weight-loss drugs?](https://directanswersrx.com/answers/glp1-side-effects): Per the FDA-approved Wegovy label, the most common side effects at incidence ≥5% are nausea, diarrhea, vomiting, constipation, and abdominal pain, along with headache, fatigue, indigestion, dizziness, bloating, burping, flatulence, gastroenteritis, GERD, and nasopharyngitis; the label also carries a…
- [Who qualifies for a GLP-1 weight-loss prescription?](https://directanswersrx.com/answers/who-qualifies-for-glp1-weight-loss): Under the FDA-approved Wegovy label, adults with obesity (BMI ≥ 30) qualify, as do adults with overweight (BMI ≥ 27) who also have at least one weight-related condition such as high blood pressure, type 2 diabetes, or high cholesterol; pediatric patients aged 12 and older with obesity also qualify.
- [Is telehealth-prescribed compounded semaglutide legitimate?](https://directanswersrx.com/answers/is-telehealth-glp1-legitimate): Not exactly — compounded semaglutide sold by telehealth clinics is not FDA-approved and, as of the FDA's February 6, 2026 announcement, the agency intends to restrict the active ingredients used to make it — a signal that the era of freely mass-marketed compounded GLP-1s is closing.
- [What has Congress said about Ozempic pricing?](https://directanswersrx.com/answers/what-congress-said-about-ozempic-pricing): On September 24, 2024, the U.S. Senate Committee on Health, Education, Labor and Pensions held a hearing focused specifically on why Novo Nordisk charges Americans far more for Ozempic and Wegovy than patients pay in other high-income countries, and pressed the company on whether U.S. list prices co…